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Subject: Re: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Date: Monday, October 12, 2015 4:55:36 PM
Author: Alan Hall <ahalltoxic**At_Symbol_Here**GMAIL.COM> 		Next by Date:
Subject: Re: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Date: Tue, 13 Oct 2015 13:33:02 +0000
Author: "Tobias, Bruce"

From: Louis DiBerardinis <loudib**At_Symbol_Here**MIT.EDU>
Subject: Re: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Date: Tue, 13 Oct 2015 11:33:05 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: B0293D9281F2FF48A8D680CCDCE21166012C7A7CCD**At_Symbol_Here**OC11EXPO33.exchange.mit.edu
In-Reply-To <71E50DF480EFA64BA856FD3CB7B11BE1ECCEFA08**At_Symbol_Here**BUTKUS.anl.gov>


It has only happened a couple of times but in each case we hired a toxicologist ( retired from Polaroid who did this for them ).

 

Lou

 

From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**med.cornell.edu] On Behalf Of Rupkey, Steve
Sent: Monday, October 12, 2015 10:59 AM
To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
Subject: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.

 

Greetings:

 

What do others do to assess, predict and assign an OSHA 2012 health hazard classification to a newly synthesize compound develop by your home institution when you are required to develop a SDS?  

 

I'm not so concerned about assessing the hazards of mixtures of known chemicals but concerned more about new compounds, where the new compound has no history of a health hazard evaluation and where using the precursor chemicals is not as reliable predictor of its health hazards/toxicity. 

 

Does anyone use a toxicologist to review the chemical structure of the new compound to predict and present their "best judgment" regarding the health hazard classifications? 

 

Sincerely, 

Steve Rupkey, CIH

Argonne National Laboratory

srupkey**At_Symbol_Here**anl.gov

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