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Subject: [DCHAS-L] My Toxicity
Date: Monday, October 12, 2015 8:37:00 AM
Author: Nickie Norton <nnorton**At_Symbol_Here**SHEPCHEM.COM> 		Next by Date:
Subject: Re: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Date: Mon, 12 Oct 2015 15:55:36 -0500
Author: Alan Hall

From: "Rupkey, Steve" <srupkey**At_Symbol_Here**ANL.GOV>
Subject: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Date: Mon, 12 Oct 2015 14:58:42 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: 71E50DF480EFA64BA856FD3CB7B11BE1ECCEFA08**At_Symbol_Here**BUTKUS.anl.gov


Greetings:

 

What do others do to assess, predict and assign an OSHA 2012 health hazard classification to a newly synthesize compound develop by your home institution when you are required to develop a SDS?  

 

I'm not so concerned about assessing the hazards of mixtures of known chemicals but concerned more about new compounds, where the new compound has no history of a health hazard evaluation and where using the precursor chemicals is not as reliable predictor of its health hazards/toxicity. 

 

Does anyone use a toxicologist to review the chemical structure of the new compound to predict and present their "best judgment" regarding the health hazard classifications? 

 

Sincerely, 

Steve Rupkey, CIH

Argonne National Laboratory

srupkey**At_Symbol_Here**anl.gov

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