From: Ian Zastrow <ianzastrow**At_Symbol_Here**GMAIL.COM>
Subject: [DCHAS-L] Ethyl Acetate experience Q
Date: Fri, 29 Jul 2022 15:49:17 -0700
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Message-ID: CAB2m+6_k_QvxkyBkQ+_NaB4+w9-H5k1to8Man3BBpKB1=ZP1BA**At_Symbol_Here**mail.gmail.com
In-Reply-To <699216FF-CDF2-492F-B157-B1E1EEEAE241**At_Symbol_Here**dchas.org>


Good afternoon, I have a question for the group:
Does anyone have experience using Ethyl Acetate in large quantities?
I have run extraction using Ethyl acetate as a primary solvent and some actetylation. 4x 200L reactors. Ventilation in iso8.
Have not had any problems.

What are risks to lab employees with regards to possible inhalation exposure?
I have been asked to contribute as a consultant to a phytochemical extraction facility and there ventilation is c1d2...yet I would guess that is questionable.

Does Ethyl acetate present a major health risk to employees (55 gallon size batches) with likely vapor inhalation exposure?
EPA and SDS data sheets are a bit lacking and contradicting for me to hold a strong stance on this other than full iso8 and limit all exposure with best practices.
I would like to get some personal experience and anecdotal opinions.

Assuming full face respirators are used with organic vapor cartridges, would this not be safe?
Thank you for any input.





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