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Previous by Date: Subject: Re: [DCHAS-L] chemical reactivity - hazard evaluation Date: Friday, January 14, 2022 at 10:11:38 AM Author: Jack Reidy <jreidy2**At_Symbol_Here**STANFORD.EDU> |
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Hi,
Please also see this page -
https://guides.library.stanford.edu/lab-safety/recognize-hazards/reactive-substances - which has resources about reactive substances and reactivity resources that also includes key databases such as Science of Synthesis, SciFinder, and Reaxys.
Best regards,
GB
Grace Baysinger
Chemistry & Chemical Engineering Librarian, Stanford University (Emerita)
ORCID: 0000-0003-2570-9123
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
On Behalf Of Jack Reidy
Sent: Friday, January 14, 2022 7:12 AM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: Re: [DCHAS-L] chemical reactivity - hazard evaluation
I second that, and also recommend Wiley's Guide to Chemical Incompatibilities, the Encyclopedia of Reagents for Organic Synthesis (EROS), and Fieser and Fieser's Reagents for Organic Synthesis. For a compendium of synthetic chemistry information,
I like March's Organic Synthesis, though I will confess part of that is A. stubbornness to get my money's worth since I had to buy it in undergrad and B. it's very satisfying to thump a 2000+ page book down on your desk. Joking aside, it has a huge amount
of information on both general principles and specific synthetic strategies.
Sincerely,
Jack Reidy (he/him)
Research Safety Specialist, Assistant Chemical Hygiene Officer
Environmental Health & Safety
Stanford University
484 Oak Road, Stanford, CA, 94305
Tel: (650) 497-7614
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
On Behalf Of lhlatimer**At_Symbol_Here**MINDSPRING.COM
Sent: Thursday, January 13, 2022 5:02 PM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: Re: [DCHAS-L] chemical reactivity - hazard evaluation
Melinda,
While you're waiting to get a taste of Harry's course, you might consider the last 10 years of Organic Syntheses, a series going back over 70 years. !0-20
years ago they began requiring safety discussions in all the preps accepted. They can provide your students with real world examples the students are likely to encounter in lab work in synthesis.
Since synthesis is exactly what the word means, many of the compounds and reactions are highly experimental, and may involve issues that have to be recognized
and thought about. For that situation, textbooks and references like Bretherick's are not so useful. Intuition, hazard appreciation and recognition are invaluable, and are mostly learned with others through discussions. I encourage you to include researchers
at your institution to come and talk about their work making never before made compounds by new methods.
I hope it goes well for you.
Lee Latimer
A 50+ year organic synthesis chemist.
-----Original Message-----
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Sent: Jan 13, 2022 1:41 PM
To: <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Subject: Re: [DCHAS-L] chemical reactivity - hazard evaluation
Melinda
I believe the Division's workshop on the chemical reactivity hazard, presented by Harry Elston, addresses a lot of this. It is on the schedule for the spring group of workshops.
Let me know if you have any questions.
Neal
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
On Behalf Of Melinda Box
Sent: Thursday, January 13, 2022 11:38 AM
To:
DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: [DCHAS-L] chemical reactivity - hazard evaluation
Hi, all,
I am reaching to get your idea, suggestions, and experiences with regard to reactivity hazard evaluation. I recently discovered how very unhelpful CAMEO and Bretherick's are for
evaluating research in organic synthesis or even compounds involved in drug manufacturing and am wondering what other recommendations people might make for resources to include in a hazard evaluation curriculum being designed for undergraduate and graduate
Chemistry researchers.
Thanks in advance for any input you might offer,
Melinda Box, MEd, CCHO
Organic Chemistry Lab Supervisor
Chem Dept Safety Officer
North Carolina State University
Department of Chemistry
Fox 328
Tel: (919) 515-2537
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