Chemical Safety Headlines From Google
Wednesday, January 20, 2021 at 6:34:07 AM
A service of the ACS Division of Chemical Health and Safety
Connecting Chemistry and Safety at http://www.dchas.org
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Table of Contents (5 articles)
EXPLOSIVE HAZARD IDENTIFICATION IN PHARMACEUTICAL PROCESS DEVELOPMENT: A NOVEL SCREENING METHOD AND WORKFLOW FOR SHIPPING POTENTIALLY EXPLOSIVE MATERIALS
Tags: laboratory, discovery, environmental, pharmaceutical
DOWNED UTILITY POLE SPILLS 50 GALLONS OF OIL IN SOUTH BOSTON, PROMPTS HAZMAT RESPONSE ‰?? NBC BOSTON
Tags: us_MA, public, release, response, unknown_chemical
BENDIGO HAZMAT INCIDENT SEES WOMAN TAKEN TO HOSPITAL
Tags: Australia, public, release, injury, unknown_chemical
PETROLEUM INCIDENT IN EUREKA
Tags: us_CA, public, release, response, gasoline
MASSIVE FIRE IN ERNAKULAM GUTS TWO FACTORIES AT EDAYAR INDUSTRIAL AREA
Tags: India, industrial, fire, response, solvent
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EXPLOSIVE HAZARD IDENTIFICATION IN PHARMACEUTICAL PROCESS DEVELOPMENT: A NOVEL SCREENING METHOD AND WORKFLOW FOR SHIPPING POTENTIALLY EXPLOSIVE MATERIALS
https://pubs.acs.org/doi/10.1021/acs.oprd.0c00467
Tags: laboratory, discovery, environmental, pharmaceutical
When a material is identified as potentially capable of explosive propagation by the Yoshida correlation, process safety scientists have few options for semiquantitatively assessing the hazards associated with the use of that material. Oxygen balance calculations, the Rule of 6, and the United Nations (U.N.) explosive functional group list are commonly employed qualitative/semiquantitative methods to assess explosivity without requiring additional experimental data.
In contrast, a full United Nations Transportation of Dangerous Goods testing regimen requires, at a minimum, 2 kg of material for Test Series 1 alone, an excessive amount that is rarely available in early pharmaceutical development. A new assessment, called the O.R.E.O.S. method, has been developed that combines the three traditional methods for screening of explosive properties (Oxygen balance calculations, the Rule of 6, and the Explosive functional group list) with the Onset of decomposition determined by differential scanning calorimetry and the proposed Scale.
This new assessment has been applied to known energetic materials that are flagged as potentially capable of explosive propagation by the Yoshida correlation and has been shown to be effective at classifying materials in a scale-dependent manner. The tool is customizable to fit any organization‰??s internal guidance on handling energetic materials. This assessment should find wide utility in both pharmaceutical development groups and contract research organizations as a means to classify compounds that may require further testing before scale-up or to steer project teams to discover safer alternatives. A brief description of the challenges associated with transporting materials for U.N. Series Testing is also presented with the aim of demystifying the process for obtaining such valuable data.
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DOWNED UTILITY POLE SPILLS 50 GALLONS OF OIL IN SOUTH BOSTON, PROMPTS HAZMAT RESPONSE ‰?? NBC BOSTON
https://www.nbcboston.com/news/local/downed-utility-pole-spills-50-gallons-of-oil-in-south-boston-prompts-hazmat-response/2282745/
Tags: us_MA, public, release, response, unknown_chemical
A downed utility pole with a transformer was knocked over Monday night in South Boston, spilling around 50 gallons of mineral oil and blocking one of the city's streets, the Boston Fire Department said.
The incident at 56 Ellery Street, which is near Andrew Station on the MBTA's Red Line, happened around 8 p.m. and prompted a Level 2 Hazmat response, fire officials said on Twitter.
Power had to be shut down, and Eversource crews have joined Hazmat technicians on scene to clean up and remove the pole, Boston Fire said.
The fire department did not immediately say what knocked the utility pole over.
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BENDIGO HAZMAT INCIDENT SEES WOMAN TAKEN TO HOSPITAL
https://www.bendigoadvertiser.com.au/story/7092165/woman-taken-to-hospital-after-man-sprays-unknown-substance-in-foyer-police-say/
Tags: Australia, public, release, injury, unknown_chemical
POLICE are investigating after a man sprayed an unknown substance in a premises in Bendigo, leading to a woman being taken to hospital.
Officers said the man first came into the premises on King Street with a baseball bat on Tuesday. They said the man made no threats, but was asked to get rid of it.
Police said he returned a short time later and sprayed the foyer of the premises with an unknown substance.
The foyer was then evacuated and police and firefighters were called to the scene. Fire Rescue Victoria crews treated the scene, which was deemed safe and staff allowed back in.
Paramedics took a woman in her 20s to hospital after the incident, in what appeared to be a stable condition.
A police investigation into the incident continues.
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PETROLEUM INCIDENT IN EUREKA
https://lostcoastoutpost.com/hazmat/21-0258/
Tags: us_CA, public, release, response, gasoline
A new hazardous materials incident involving petroleum has been reported to the California Office of Emergency Services.
According to a report published by the office, the incident took place at or near waterways in Eureka at around 4:10 p.m. today.
About 90 gallons of a substance described as ‰??gasoline‰?? were released to the environment, according to the person who called in the report.
This was the third hazardous materials incident recorded by the Office of Emergency Services in the Eureka area this year and the fifth petroleum spill in the county overall.
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MASSIVE FIRE IN ERNAKULAM GUTS TWO FACTORIES AT EDAYAR INDUSTRIAL AREA
https://www.thenewsminute.com/article/massive-fire-ernakulam-guts-two-factories-edayar-industrial-area-141628
Tags: India, industrial, fire, response, solvent
A massive fire that broke out in Ernakulam‰??s Edayar industrial belt in the wee hours of Saturday night, gutted two factories in the region. The fire that broke out in Orion Chemicals, an organic solvent factory later spread to the nearby rubber processing factory. According to the police, no casualties have been reported.
Edayar industrial belt is a region along the Periyar River near Eloor. The area is home to hundreds of industries. Visuals of the incident circulating on social media show dense smoke emanating from the factories. In one of the videos, a huge ball of fire can be seen rising up from the factory amidst the smoke.
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