From: "Reinhardt, Peter" <peter.reinhardt**At_Symbol_Here**YALE.EDU>
Subject: [DCHAS-L] Serious Explosion during Large-Scale Preparation of an Amine
Date: Sat, 25 Jul 2020 17:10:52 +0000
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Message-ID: BN8PR08MB628909ED84AD5F1C56289BE692740**At_Symbol_Here**BN8PR08MB6289.namprd08.prod.outlook.com
In-Reply-To



Peter A. Reinhardt
Director, Yale Office of Environmental Health & Safety
203-737-2123

Please see the following description of a serious incident during an Alane-based reduction of a nitrile:

 

"Serious Explosion during Large-Scale Preparation of an Amine by Alane (AlH3) Reduction of a Nitrile Bearing a CF3 Group" https://pubs.acs.org/doi/pdf/10.1021/acs.chas.0c00045

 

The article contains a number of useful points.

Please share with your research groups.

 

Previous post   |  Top of Page   |   Next post



The content of this page reflects the personal opinion(s) of the author(s) only, not the American Chemical Society, ILPI, Safety Emporium, or any other party. Use of any information on this page is at the reader's own risk. Unauthorized reproduction of these materials is prohibited. Send questions/comments about the archive to secretary@dchas.org.
The maintenance and hosting of the DCHAS-L archive is provided through the generous support of Safety Emporium.