Based on a recent trip I made to Africa, industrialization & development is likely to be an attraction to people on the bottom of the economic barrel in a country. It's a problem that is not easily solved.--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here**dchas.org Follow us on Twitter **At_Symbol_Here**acsdchasAlso, with respect to Bhopal, regardless of how the incident was caused (whether by sabotage or otherwise), the fact remains that multiple safety systems at the facility were disabled, any of which might have prevented the scope of the tragedy.Richard Rosera
Board Member and Executive AdvisorEHS GRADES InternationalPhone: 713-730-2733
Direct: 908-279-4463Fax: 713-730-2734On Feb 6, 2019, at 11:42 AM, Monona Rossol <0000030664c37427-dmarc-request**At_Symbol_Here**LISTS.PRINCETON.EDU> wrote:Alan,
Can't believe you said this. Go see.Maybe squatters should not move in next door to a chemical plant?
And the lawsuits filed after and even still today have to do with continuing health issues and sensitization. So this is another problem that won't go away until the last Bhopal victim, and perhaps their fist generation children are dead and gone.--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here**dchas.org Follow us on Twitter **At_Symbol_Here**acsdchas
Monona
-----Original Message-----
From: Alan Hall <oldeddoc**At_Symbol_Here**GMAIL.COM>
To: DCHAS-L <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Sent: Wed, Feb 6, 2019 1:02 pm
Subject: Re: [DCHAS-L] Question on triglycidyl isocyanurate (TGIC)
Et al,In general (not necessarily speccific to the compound in question), most isocyanurates are sensitizers. This means that a single high-level airborne exposure can cause RADS (Reactive Airways Dysfunction Syndrome) or in others with more low-level chronic exposure, Occupational Asthma (there are specific published critera for this diagnosis), and there's a few who don't any meet all of the criteria and still are disabled.That whole disaster in Bhopal was with MIC. I've had to review every bit of the data. It causes pulmonary edema which was fatal in many cases.. There was no cyanide release. Maybe squatters should not move in next door to a chemical plant? It was there first. But a true tragedy and if a couple disgruntled employees had not done the wrong thing, it mght never have happened and the world would be a better place.Free medical advice is worth exactly what you pay for it, but if I had worn your mocassins and walked a mile, I think I'd consult the folks at the Johns Hopkins in Baltimore and go from there. Sir Osler founded the bedside teaching of medicine in America, and there's some darned good folks still there. There's some tests might done and maybe an improved treatment regimen.AlanAlan H. Hall, M.D.Medical ToxicologistToxicology Consulting and Medical Translating ServicesSpringtown and Azle, TexasClinical Assistant ProfessorColorado School of Public HealthUniversity of Colorado-Denver
--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here**dchas.org Follow us on Twitter **At_Symbol_Here**acsdchasOn Wed, Feb 6, 2019 at 9:30 AM TILAK CHANDRA <0000058f112ac338-dmarc-request**At_Symbol_Here**lists.princeton.edu> wrote:--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here**dchas.org Follow us on Twitter **At_Symbol_Here**acsdchasIsocyanates are also precursor for many pesticides. Methyl isocyanate (MIC) killed around 10,000 people in Bhopal in 1984 (Union carbide incident). It means some of the isocyanate can be lethal.TilakFrom: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON..EDU> On Behalf Of Monona Rossol
Sent: Tuesday, February 05, 2019 1:56 PM
To: DCHAS-L**At_Symbol_Here**PRINCETON.EDU
Subject: Re: [DCHAS-L] Question on triglycidyl isocyanurate (TGIC)Of course it is. We need to look at adopting the UK rules for this whole bunch of chemicals. They don't care what isocyanate radical is attached to, it is regulated as a sensitizer whether it has actually been tested and found so or not.
Monona Rossol, MS, MFA, Industrial Hygienist-----Original Message-----
From: Wisnewski, Adam <adam.wisnewski**At_Symbol_Here**YALE.EDU>
To: DCHAS-L <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Sent: Tue, Feb 5, 2019 2:47 pm
Subject: Re: [DCHAS-L] Question on triglycidyl isocyanurate (TGIC)Here is a case series report JACI in Practice...It is a sensitizerAdam V Wisnewski, PhDSenior Research ScientistDepartment Internal Medicine/Section General MedicineProgram in Occupational & Environmental MedicineYale School of Medicine300 Cedar Street/PO Box 208057Building: TACS420New Haven, CT 06520-8057203-737-4054 (lab)203-645-5665 (cell)
From: Bello, Dhimiter <Dhimiter_Bello**At_Symbol_Here**uml.edu>
Sent: Tuesday, February 5, 2019 1:52 PM
To: Redlich, Carrie; Wisnewski, Adam
Subject: Fwd: [DCHAS-L] Question on triglycidyl isocyanurate (TGIC)This was on my draft folder-FYISent from my iPhonePlease excuse typos and brevity.
Begin forwarded message:From: Boitumelo Kgarebe <bkgarebe**At_Symbol_Here**GMAIL.COM>
Date: September 17, 2018 at 8:44:00 AM EDT
To: <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Subject: Re: [DCHAS-L] Question on triglycidyl isocyanurate (TGIC)
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>Dear Colleagues,Our Occupational Medicine clinic saw two patients who were from the same company, performing the same duties, namely powder spray coating using a chemical called triglycidyl isocyanurate (TGIC). They were assessed and the clinic seemed convinced that this chemical is a sensitizer, causing their occupational condition.A factory visit to understand exposures and associated occupational setting well, was also undertaken . The process observed was similar to what is described in literature.The Factory Management seems to be keen that we investigate this further, as they are adamant this chemical is not the likely cause of their respiratory (asthmatic) effects. Another point from the company is that the TGIC is actually bound to a resin thus not active on its own as it is already in a bound state (not freely available).My question is: Is TGIC found in the sample/ that they use is freely available as a sensitiser? Are there other less harmful substitutes?BVKDr Boitumelo V. Kgarebe Phd(London) FAASHead: Analytical Services25 Hospital Street, JHB 2001National Institute for Occupational HealthNational Health Laboratory ServiceTel: +27(0)11 712 6410 | Mobile: +27(0)82 | Fax: +27(0) 712 6545--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here**dchas.org Follow us on Twitter **At_Symbol_Here**acsdchas--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here**dchas.org Follow us on Twitter **At_Symbol_Here**acsdchas--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here**dchas.org Follow us on Twitter **At_Symbol_Here**acsdchas
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