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Previous by Date: Subject: Re: [DCHAS-L] Lone Worker Policy Date: Monday, January 11, 2016 6:58:46 PM Author: Monona Rossol <actsnyc**At_Symbol_Here**cs.com> |
Next by Date: Subject: Re: [DCHAS-L] Lone Worker Policy Date: Tue, 12 Jan 2016 01:12:23 +0000 Author: Debbie M. Decker |
Isn't that lovely. These agencies band together in this press release in which they identify the problems with in vitro testing. There are similar inadequacies for the in silico predictions. And all these agencies want to do is find better ways of predicting. How about actually testing the chemicals?
The E.U. provided an answer to the lack of data in 2008 when they gave industry until 2018 to provide the data from the standard 10 tox test required on the SDS on the 30,000 high production volume chemicals. At that time, their "no test, no market" policy would be in effect. But our industries decided that none of the profit from selling over 1000 tons a year of each of these chemicals/year for decades should be used to pay the roughly $100,000 cost/chemical to test. And nobody says boo.
Now the TTIP treaty will probably have a provision that will force the E.U. to accept products that meet our "standards" (and we don't have any standards for tox testing) instead of testing. And there goes game.
The more animal test data we have, the better we can make the in vitro and in silico systems. But first, we need some real data. These agencies should get together and tell industry they really should test 30,000 of the 143,000 chemicals registered for use in the E.U. consumer market---chemicals in products that most of the world's inhabitants are being exposed to. It's the least the chemical industry can do.
Monona Rossol, M.S., M.F.A., Industrial Hygienist
President: Arts, Crafts & Theater Safety, Inc.
Safety Officer: Local USA829, IATSE
181 Thompson St., #23
New York, NY 10012 212-777-0062
-----Original Message-----
From: Secretary, ACS Division of Chemical Health and Safety <secretary**At_Symbol_Here**DCHAS.ORG>
To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Sent: Mon, Jan 11, 2016 5:03 pm
Subject: [DCHAS-L] Transform Tox Testing Challenge: Innovating for Metabolism
NLM Toxicology and Environmental Health Info
The U.S. Environmental Protection Agency (EPA), the U.S. National Institutes of Health's (NIH) National Center for Advancing Translational Sciences (NCATS), and the NIH's National Toxicology Program (NTP) have announced a challenge that will award up to $1 million to improve the relevance and predictivity of data generated from automated chemical screening technology used for toxicity testing.
Out of thousands of chemicals in use today, very few have been fully evaluated for potential health risks. A majority of in vitro high-throughput screening (HTS) assays used to test chemicals for potential toxicity lack metabolic competence. While existing technologies could help fill this gap, these technologies are not currently adapted to allow metabolic transformations in HTS systems (i.e. cell-based assays).
The goal of this challenge is to develop a practical design that will turn existing, commonly used in vitro chemical screening assays into tests competent enough to produce physiologically relevant metabolites within cell-based HTS assays which will evaluate both parent chemical and metabolite effects in the assay responses.
The successful design will offer information that can be used to review and evaluate HTS assay results, and will also ensure better quality data, transparency, and overall confidence in assay results.
For more information on the Tox Testing Challenge: https://urldefense.proofpoint.com/v2/url?u=http-3A__www.transformtoxtesting.com&d=BQIFaQ&c=lb62iw4YL4RFalcE2hQUQealT9-RXrryqt9KZX2qu2s&r=meWM1Buqv4IQ27AlK1OJRjcQl09S1Zta6YXKalY_Io0&m=G6sRy1rs_tP1PkGJ1A3yhrZuFmDd6_LyTsFgNou0iL0&s=m_dJmK24uyo_Sr-p5Uvfw6o9OlcBS6qLqYHtp_N7-jg&e=
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