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Previous by Date: Subject: [DCHAS-L] CSB Deploys to Chemical Spill in Charleston, WV Date: Sunday, January 12, 2014 9:11:43 AM Author: "Secretary, ACS Division of Chemical Health and Safety" <secretary**At_Symbol_Here**DCHAS.ORG> |
Next by Date: Subject: Re: [DCHAS-L] Chemical Leak in WV Date: Sun, 12 Jan 2014 10:04:21 -0500 Author: Monona Rossol |
A denaturing agent? Wow. I didn't know that. That would have added an interesting footnote to a number of parties when I was in school.
Feen-a-Mint now contains bisacodyl. Unfortunately, bisacodyl is also a derivative of diphenylmethane and structurally similar to phenolphthalein. It has not been tested for cancer effects. In fact, it is used in treatment of colon cancer. A couple epi studies looked at colorectal cancers in bisacodyl users. But when phenolphthalein was studied, colon cancers were not one of the types of cancer seen in the animals. I did see one sort of epi study questioning whether bisacodyl was related to renal cancers seen in users. That's more likely actually.
There have been some survey studies of bisacodyl use in pregnancy and birth defects in the offspring. But I couldn't find any follow up for later cancer effects in either mom's or offspring.
When you see a controlled drug insert, it will tell you in fine print what tests have NOT been done. But OTC products usually just omit the information about lack of testing.
Clearly, there should be a full evaluation of this and similar chemicals with 2-year, 2-species animal tests.
Think roughage, my friends, roughage.
Monona Rossol, M.S., M.F.A., Industrial Hygienist
President: Arts, Crafts & Theater Safety, Inc.
Safety Officer: Local USA829, IATSE
181 Thompson St., #23
New York, NY 10012 212-777-0062
-----Original Message-----
From: alvaldenio <alvaldenio**At_Symbol_Here**VERIZON.NET>
To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Sent: Sun, Jan 12, 2014 9:11 am
Subject: Re: [DCHAS-L] Chemical Leak in WV
Phenolphthalein was the active ingredient in Feenamint (Spelling?). It was also used to "denature" ethanol in student labs years ago. Al Denio, Newark, DE
On 01/11/14, Monona Rossol<actsnyc**At_Symbol_Here**CS.COM> wrote:
Manona [sic Monona] notes that "at 10 ppm or so it is pretty innocuous by ingestion" is an unsupported claim even for acute toxicity unless you can find an accepted LD50 some where which is not on the SDSs. And I sure would like to know who ingested it and got the runs. Now that's a story.. Tell the industry to provide the DATA--nice neat references and I'll back off.
It reminds me of the guy who in 1858 first synthesized phenolphthalein, drank some and got a raging case of the Aztec two-step. His response was "Eureka, I've invented a laxative," and it immediately became the most common laxative sold world wide. FDA finally got around to studying it 130 years later. When the data came out in 1992, it was found to be not only a carcinogen, but one of the most potent ever studied producing multiple types of cancer at multiple sites. It was banned with no fanfare. The public was not even aware that the Ex-Lax they used for decades was a carcinogen.
So who knows what this rotten, licorice-smelling, ore floatation chemical can do to people? There is an experiment going on in West Virginia, and guess who the lab rats are? And instead of providing them with information so they can provide "informed consent" they are being told it is pretty innocuous. I object unless the industry can provide references. And my question to everyone, is why don't we ALWAYS demand to see the data? Aren't we chemists?
Monona Rossol, M.S., M.F.A., Industrial Hygienist
President: Arts, Crafts & Theater Safety, Inc.
Safety Officer: Local USA829, IATSE
181 Thompson St., #23
New York, NY 10012 212-777-0062
-----Original Message-----
From: Melissa Charlton-Smith <charltonsmith**At_Symbol_Here**WVWC.EDU>
To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Sent: Sat, Jan 11, 2014 9:10 am
Subject: Re: [DCHAS-L] Chemical Leak in WV
4-Methyl-1- cyclohexanemethanol of course there are multiple names for it all about the same but the CAS# is 34885-30-5 and like Manona says you really can't find much out there on it. I talked to a HazMat tech Emergency responder friend of mine who also is a certified Class III wastewater operator and he said it really depends on the levels released. It's soluble to 0.2% in water but at 10 ppm or so it is pretty innocuous by ingestion-.though it might give you a good case of the-.ummm-.runs.
Mel Charlton-Smith
WVWC Chemical Hygiene Officer-NRCC
Chemistry Lab Coordinator, Lecturer
BS-CHO Program Coordinator
Department of Chemistry
WV Wesleyan College
Buckhannon, WV 26201
304-473-8355
From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**MED.CORNELL.EDU] On Behalf Of Frankie Wood-Black
Sent: Friday, January 10, 2014 6:21 PM
To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
Subject: Re: [DCHAS-L] Chemical Leak in WV
Do you know what was released? The report I saw was that it was an antifoaming agent.
On Jan 10, 2014 4:30 PM, "Melissa Charlton-Smith" <charltonsmith**At_Symbol_Here**wvwc.edu> wrote:
Just thought I would share this with everyone from my home state
Mel Charlton-Smith
WVWC Chemical Hygiene Officer-NRCC
Chemistry Lab Coordinator, Lecturer
BS-CHO program
Department of Chemistry
WV Wesleyan College
Buckhannon, WV 26201
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