We have b een working on this issue for the past year also. < /p>
We changed the IACUC chemical hazard form that investigators fi ll out for animal protocols to include:
· Marking substances as carcinogens, toxics, reprod
uctive hazards, cytotoxic/antineoplastic agents, investigational drugs with
limited safety data, and/or nanoparticles or nanoparticle formulation.
· ;   ; Based on what the y mark on the form our animal husbandry staff now designate certain cages a s chemical hazards, post the door and treat the waste (cages/bedding/water bottles/carcasses) differently.
· Split the risk assessment section up into “M aterials Handling/Administration” and “Cage Changing” so that both researchers and husbandry staff are addressed p>
We have also started writing SOPS for specific hazardous chemica ls used in animals that address issues related to both researchers and husb andry staff.
-Cathy
Catherine
R. Brennan
Chemical Hygiene Officer
CB#1650
Environment, Health and Safety
1120 Este
s Drive Extension
University of North Ca rolina at Chapel Hill
Chapel Hill, NC 27599-1650
(919) 843-5331
(919) 962-0227 FAX
From:
DCHAS-L
Discussion List [mailto:DCHAS-L**At_Symbol_Here**list.uvm.edu] On Behalf Of Kohler,
Christopher E
Sent: Thursday, December 09, 2010 1:25 PM
To:
DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Subject: Re: [DCHAS-L] Chemical Safety
and Lab Animals
We are working this out as we s peak. Very timely question.
From a chemical h ygiene standpoint I want the researchers, in their animal use protocols, to provide hazard info and/or LD50 info for all chemicals used in protocols t o assess the chemical handling requirements for those chemicals under the l ab standard.
If the fall into OSHAs “p articularly hazardous substances” (carcinogens, reproductive toxins, or acutely toxic chemicals) then they should be handled in a containment (i f decanted) or a closed system (syringe or gavage).
< p class="MsoNormal">We also look for compliance with the use of controlled substances a t that time and any issues for waste handling of bedding or animal carcasse s for the animal care personnel.
Chris
Christopher E. Kohler
Certified Chemical Hygiene Officer
Laboratory Safety Manager
Indiana University
Office of Environmental, Health, and Safety Management
1514 East Third Street
Bloomington, IN 47405
(812) 855-6311
From: DCHAS-L Discussion List [mailto:DCHAS-L**At_Symbol_Here**L
IST.UVM.EDU] On Behalf Of Johnson, Amy Carr
Sent: Thursday
, December 09, 2010 12:21 PM
To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Subje
ct: [DCHAS-L] Chemical Safety and Lab Animals
I am try ing to get information from peer institutions about how they manage worker safety in regard to exposure to chemicals administered to lab animals.  ; Does anyone have any expertise in this issue?
Thank you-< /p>
Amy Johnson
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