Good question George, I didn't fill in all the facts... The gloves she wore did not extend to the elbow. The material in fact dribbled from her gloves to her arm. She was wearing eye protection as well and I believe she as working in a fume hood but I'll have to verify that. -Russ Russell Vernon, Ph.D. Research Safety Environmental Health & Safety University of California, Riverside 900 University Ave Riverside, CA 92521 www.ehs.ucr.edu russell.vernon**At_Symbol_Here**ucr.edu Direct (951) 827-5119 Admin (951) 827-5528 Fax (951) 827-5122 -----Original Message----- From: DCHAS-L Discussion List [mailto:DCHAS-L**At_Symbol_Here**list.uvm.edu] On Behalf Of George D. McCallion Sent: Friday, September 24, 2010 2:42 AM To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU Subject: Re: [DCHAS-L] BOC clevage safety protocols My first question is: where was the PPE? As for a written protocol, I would include working within a VBE (vent. balance enclosure), gloves and safety glasses... I am certain others here have more feedback... Sincerely, george George D. McCallion Chemist III Chemical Process Research & Development Johnson Matthey Pharmaceutical Materials 2003 Nolte Drive West Deptford, NJ 08066-1742 Voice: 856.384.7255 Fax: 856.384.7186 E-Mail: medchem**At_Symbol_Here**comcast.net ************************************************************************ ********* On Sep 23, 2010, at 9:38 PM, Russell Vernon wrote: > Dear Fellow Chemists, > > A researcher at one of our sister campuses was using a needless > syringe filled with a solution of 36 mL TFA, 2 mL thioanisole, 1.2 > mL ethane dithiol, and 0.8 mL anisole, She inadvertently expelled a > portion which impacted her elbow. She very quickly washed the > exposure with copious water. The skin became seriously discolored > and it is likely the treatment will include skin grafts. > > This isn't my area of expertise but from what I read it is a common > protecting group cleavage cocktail for protein synthesis. > > If any of you have any written procedures that would improve the > process we would appreciate getting a copy. > > Sincerely, > -Russ > > > Russell Vernon, Ph.D. > Research Safety > Environmental Health & Safety > University of California, Riverside > 900 University Ave > Riverside, CA 92521 > www.ehs.ucr.edu > russell.vernon**At_Symbol_Here**ucr.edu > > Direct (951) 827-5119 > Admin (951) 827-5528 > Fax (951) 827-5122
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