Nick, Number one, toxicities CANNOT be compared. If x has an LD50 of, say, 100 mg/kg and y has a toxicity of 200 mg/kg, you cannot say that one is twice as toxic as the other because x is toxic, say, to the liver, whereas y causes cancer of the epiglottis. Number two, to measure toxicities you need some test animals and the associated resources for the animal care and appropriate laboratory observations and conclusions. One can buy these on the open market; the cost is not small. Number three, just because the names are related does not in any way indicate that the toxicities will be related. Jay Young *********************************** ----- Original Message ----- From: "Tsiakals, Nicholas John"To: Sent: Thursday, June 10, 2010 5:30 PM Subject: [DCHAS-L] toxicity question > Good afternoon all, > > How does toxicity compare from one pharmaceutical salt to another? More > specifically, is the toxicity of norepinephrine the same as norepinephrine > bitartrate salt? > > Thanks, > -Nick >
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